Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 4/20 | 0.42 |
| ▸ | HMGCR | P04035 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043689 | 1.00 | PTPN7 (0.42) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL8024226 | 0.98 | LMNA (0.39) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL23034432 | 0.84 | LMNA (0.41) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL15506096 | 0.82 | PTPN7 (0.39) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL25735589 | 0.82 | PTPN7 (0.39) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL23015071 | 0.81 | LMNA (0.32) | LMNA | |
| SCHEMBL23014741 | 0.80 | CES1 (0.36) | LMNAFAAHCES1CES2 | |
| SCHEMBL23014991 | 0.80 | CES2 (0.37) | THRBLMNACES1CES2 | |
| SCHEMBL23034420 | 0.78 | LMNA (0.44) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL28926115 | 0.78 | LMNA (0.44) | PTPN7HMGCRRECQLTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330491-B1 | NOVEL LIQUID CRYSTAL COMPOUNDS | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1993-04-28 | — | — | EP | claimed |