Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024513 | 0.92 | PKM (0.33) | PKMPTGS1 | |
| SCHEMBL8020546 | 0.85 | ALDH1A1 (0.36) | PKMMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8022702 | 0.84 | PTGS1 (0.35) | PKMPTGS1ACHEMEN1NPC1 | |
| SCHEMBL8020542 | 0.77 | ALDH1A1 (0.35) | PKMMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8022699 | 0.75 | PTGS1 (0.34) | PKMPTGS1ACHEMEN1NPC1 | |
| SCHEMBL8206762 | 0.74 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL26416220 | 0.71 | NPC1 (0.39) | PKMACHEMEN1NPC1RAB9A | |
| SCHEMBL26419875 | 0.70 | FFAR1 (0.46) | PKMMEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL26419706 | 0.69 | MAPT (0.41) | ACHEMEN1KMT2AKDM4E | |
| SCHEMBL8026649 | 0.68 | NOTUM (0.42) | ACHEMEN1RAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975587-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998043949-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-08 | — | — | WO | disclosed |