SCHEMBL8206762

SCHEMBL8206762

COC=C(Oc1cc(CC=NOC[Si](C)(C)c2ccccc2)ccc1C)C(=O)OC

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020542 0.86 ALDH1A1 (0.35) MEN1KMT2ACYP3A4TDP1L3MBTL1
SCHEMBL8024513 0.82 PKM (0.33)
SCHEMBL8022699 0.79 PTGS1 (0.34) MEN1KMT2ACYP3A4TDP1L3MBTL1
SCHEMBL8020546 0.78 ALDH1A1 (0.36) MEN1KMT2ACYP3A4TDP1L3MBTL1
SCHEMBL26418778 0.76 MPO (0.39) MEN1KMT2ATDP1L3MBTL1MAPT
SCHEMBL8024516 0.74 PKM (0.34) MEN1KMT2A
SCHEMBL26418764 0.73 FFAR1 (0.44) MEN1KMT2ATDP1MAPT
SCHEMBL23712445 0.73 CYP4F2 (0.40) MEN1KMT2ATDP1L3MBTL1MAPT
SCHEMBL26418742 0.72 PKM (0.39) MEN1KMT2ATDP1L3MBTL1MAPT
SCHEMBL26416220 0.71 NPC1 (0.39) MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000297090-A OXIME ETHER COMPOUND AND USE THEREOF SUMITOMO CHEM CO LTD 2000-10-24 JP disclosed