Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018718 | 0.86 | MAOA (0.47) | TDP1ALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL9208848 | 0.81 | RELA (0.46) | TP53ALDH1A1SMN1; SMN2MAOBKDM4E | |
| SCHEMBL1314001 | 0.81 | AGXT (0.42) | TDP1ALDH1A1TSHRSMN1; SMN2MAOB | |
| SCHEMBL8149467 | 0.80 | GABRA1 (0.41) | SMN1; SMN2KDM4E | |
| SCHEMBL5871100 | 0.80 | TP53 (0.40) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL8795972 | 0.79 | TSHR (0.34) | TSHRSMN1; SMN2MAOBKDM4EPKM | |
| SCHEMBL6936162 | 0.79 | IDO1 (0.49) | MAOAMAOB | |
| SCHEMBL6622204 | 0.79 | MAOB (0.47) | MAOAMAOB | |
| SCHEMBL8024443 | 0.79 | MRGPRX4 (0.38) | TP53TSHRSMN1; SMN2 | |
| SCHEMBL29910773 | 0.79 | IDO1 (0.49) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000049020-A2 | NOVEL EPOTHILON DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL APPLICATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-08-24 | — | — | WO | disclosed |