Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 4/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11174190 | 0.84 | AHR (0.38) | MTNR1AAHR | |
| SCHEMBL29432879 | 0.81 | LIPG (0.49) | MTNR1ALIPGBIDMCL1BCL2L1 | |
| SCHEMBL7054345 | 0.81 | LIPG (0.49) | MTNR1ALIPGBIDMCL1BCL2L1 | |
| SCHEMBL18153979 | 0.81 | LIPG (0.49) | MTNR1ALIPGBIDMCL1BCL2L1 | |
| SCHEMBL28222763 | 0.79 | LIPG (0.46) | MTNR1ALIPGBIDMCL1BCL2L1 | |
| SCHEMBL27483096 | 0.77 | MTNR1A (0.41) | MTNR1ALIPGBIDMCL1BCL2L1 | |
| SCHEMBL2178352 | 0.75 | LIPG (0.47) | TBXAS1LIPGBIDMCL1BCL2L1 | |
| SCHEMBL6258218 | 0.75 | AHR (0.43) | MTNR1AAHR | |
| SCHEMBL5587846 | 0.74 | ALOX5 (0.44) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL5587771 | 0.74 | ALOX5 (0.44) | LIPGBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932601-A4 | PROCESS FOR PREPARING PHARMACEUTICAL COMPOUNDS | LILLY CO ELI (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0932601-A1 | PROCESS FOR PREPARING PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998008812-A1 | PROCESS FOR PREPARING PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |