Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248162 | 0.81 | P2RX7 (0.66) | P2RX7KDM4ETDP1MAP2K1POLB | |
| SCHEMBL27819878 | 0.81 | P2RX7 (0.66) | P2RX7KDM4ETDP1MAP2K1POLB | |
| SCHEMBL7465180 | 0.81 | SMN1; SMN2 (0.58) | TDP1POLBRAB9ANPC1HTT | |
| SCHEMBL9487126 | 0.80 | P2RX7 (0.51) | P2RX7KDM4ETDP1MAP2K1POLB | |
| Methyl Alcohol SCHEMBL27938435 | 0.80 | P2RX7 (0.64) | P2RX7KDM4ETDP1MAP2K1POLB | |
| SCHEMBL8022308 | 0.79 | P2RX7 (0.58) | P2RX7KDM4ETDP1POLBRAB9A | |
| SCHEMBL8024933 | 0.79 | P2RX7 (0.50) | P2RX7KDM4ETDP1MAP2K1POLB | |
| SCHEMBL9486140 | 0.79 | P2RX7 (0.50) | P2RX7KDM4ETDP1MAP2K1POLB | |
| SCHEMBL4414277 | 0.77 | P2RX7 (0.70) | P2RX7KDM4ETDP1RAB9AALDH1A1 | |
| SCHEMBL11078263 | 0.77 | P2RX7 (0.63) | P2RX7KDM4ETDP1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876344-B1 | PYRIDYLACETIC ACID DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AG (DE) | 2000-08-23 | — | — | EP | claimed |
| EP-0876344-B1 | PYRIDYLACETIC ACID DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AG (DE) | 2000-08-23 | — | — | EP | disclosed |
| EP-0873313-B1 | PYRIDYLACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION, AND THEIR USE | BASF AG (DE) | 2000-03-15 | — | — | EP | disclosed |
| EP-0876344-A1 | PYRIDYLACETIC ACID DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-11 | — | — | EP | disclosed |
| EP-0873313-A1 | PYRIDYLACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION, AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997017328-A1 | PYRIDYLACETIC ACID DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-15 | — | — | WO | disclosed |
| WO-1997016427-A1 | PYRIDYLACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION, AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | disclosed |