Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487126 | 0.86 | P2RX7 (0.51) | P2RX7TDP1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9486269 | 0.84 | LMNA (0.50) | CYP1A2CYP2C19POLBNPC1ALDH1A1 | |
| SCHEMBL9486264 | 0.84 | LMNA (0.50) | CYP1A2CYP2C19POLBNPC1ALDH1A1 | |
| SCHEMBL9487168 | 0.80 | P2RX7 (0.36) | P2RX7TDP1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8024718 | 0.79 | P2RX7 (0.57) | P2RX7TDP1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9487912 | 0.78 | TDP1 (0.65) | TDP1MAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL1426471 | 0.78 | NPC1 (0.43) | POLBNPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL5998808 | 0.78 | NPC1 (0.43) | POLBNPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL1426474 | 0.78 | NPC1 (0.43) | POLBNPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL9875018 | 0.76 | GAA (0.47) | TDP1MAPTPOLBNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221316-A | Insecticides, nematodes or plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-22 | — | — | US | disclosed |
| US-5112386-A | Acrylic acid derivatives containing pyridine ring, agricultural use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | disclosed |
| US-4826531-A | ACRYLIC ACID PYRIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-02 | — | — | US | disclosed |
| EP-0243012-A2 | Pyridyl-acrylic acid ester derivatives, process for their preparation and their use as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-28 | — | — | EP | disclosed |