Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022654 | 0.86 | P2RX7 (0.47) | P2RX7HIF1ATDP1KDM4ENPC1 | |
| SCHEMBL27449778 | 0.84 | LMNA (0.50) | HIF1APOLBNPC1HTTL3MBTL1 | |
| SCHEMBL8025024 | 0.81 | HIF1A (0.47) | P2RX7HIF1ATDP1KDM4EMAP2K1 | |
| SCHEMBL27451664 | 0.81 | TRPV1 (0.43) | HIF1AKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8024718 | 0.79 | P2RX7 (0.57) | P2RX7TDP1KDM4EPOLBMAP2K1 | |
| SCHEMBL29883529 | 0.78 | HIF1A (0.51) | HIF1APOLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL29445316 | 0.78 | HIF1A (0.51) | HIF1APOLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL6155893 | 0.78 | HIF1A (0.51) | HIF1APOLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL29810082 | 0.78 | HIF1A (0.51) | HIF1APOLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL3747106 | 0.78 | HIF1A (0.51) | HIF1APOLBNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876344-B1 | PYRIDYLACETIC ACID DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AG (DE) | 2000-08-23 | — | — | EP | disclosed |
| EP-0873313-B1 | PYRIDYLACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION, AND THEIR USE | BASF AG (DE) | 2000-03-15 | — | — | EP | disclosed |
| EP-0876344-A1 | PYRIDYLACETIC ACID DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-11 | — | — | EP | disclosed |
| EP-0873313-A1 | PYRIDYLACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION, AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997017328-A1 | PYRIDYLACETIC ACID DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-15 | — | — | WO | disclosed |
| WO-1997016427-A1 | PYRIDYLACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION, AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | disclosed |