Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453537 | 1.00 | PRMT1 (0.37) | PRMT1MMP2MMP7MMP9MMP13 | |
| SCHEMBL7453483 | 0.92 | ALDH1A1 (0.38) | MMP2MMP7MMP9MMP13MMP1 | |
| SCHEMBL2582026 | 0.90 | ESR1 (0.36) | MMP2MMP7MMP9MMP13MMP1 | |
| SCHEMBL7459208 | 0.89 | POLB (0.38) | MMP2MMP7MMP9MMP13MMP1 | |
| SCHEMBL7453235 | 0.88 | PRMT1 (0.40) | PRMT1BACE1ALDH1A1CA12CA1 | |
| SCHEMBL2576895 | 0.87 | MMP1 (0.47) | MMP2MMP9MMP13MMP1MMP3 | |
| SCHEMBL13673910 | 0.87 | MMP2 (0.43) | MMP2MMP7MMP9MMP13MMP3 | |
| SCHEMBL2585365 | 0.86 | KMT2A (0.42) | MMP2MMP7MMP9MMP13MMP1 | |
| SCHEMBL8501160 | 0.81 | CYP2D6 (0.50) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL13673916 | 0.81 | CYP2D6 (0.41) | NPC1RAB9AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977570-A1 | QUINOXALINE IN TRIPLE COMBINATION WITH PROTEASE INHIBITORS AND REVERSE TRANSCRIPTASE INHIBITORS AS MEDICINES FOR TREATING AIDS | BAYER AG (DE) | 2000-02-09 | — | — | EP | claimed |
| WO-1998032442-A1 | QUINOXALINE IN TRIPLE COMBINATION WITH PROTEASE INHIBITORS AND REVERSE TRANSCRIPTASE INHIBITORS AS MEDICINES FOR TREATING AIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-30 | — | — | WO | claimed |