Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 3/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.54 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037695 | 0.88 | TP53 (0.51) | HTTCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL8024318 | 0.87 | EGFR (0.51) | HTTEGFRPOLBPDE5AMAPT | |
| SCHEMBL8025185 | 0.85 | PRMT1 (0.48) | HTTEGFRPOLBMEN1KMT2A | |
| SCHEMBL8026802 | 0.84 | CDK1 (0.50) | HTTCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL29176418 | 0.79 | HTT (0.43) | HTTCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL8024930 | 0.78 | EGFR (0.48) | EGFRNR2F2AURKARPS6KB1 | |
| SCHEMBL9038905 | 0.78 | TP53 (0.51) | HTTCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL16997389 | 0.77 | PDE5A (0.60) | HTTEGFRPOLBMEN1KMT2A | |
| Flufenerim SCHEMBL26581 | 0.75 | CYP3A4 (0.42) | HTTPOLBNR2F2MEN1KMT2A | |
| Flufenerim SCHEMBL29429245 | 0.75 | CYP3A4 (0.42) | HTTPOLBNR2F2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |