SCHEMBL8024871

SCHEMBL8024871

Cc1ccc2c(c1C)C=CC2[Ti]

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALOX15 P16050 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8673204 0.98 KDM4E (0.30) KDM4EMEN1ALOX15KMT2AHSD17B10
Bromide SCHEMBL8038473 0.73 KDM4E (0.33) KDM4EMEN1ALOX15KMT2AHSD17B10
SCHEMBL8038477 0.71
SCHEMBL8024847 0.71
SCHEMBL12657230 0.63 HTR2A (0.33)
SCHEMBL29352563 0.58 TSHR (0.45) KDM4E
SCHEMBL5494672 0.58 TSHR (0.45) KDM4E
SCHEMBL2964596 0.57
SCHEMBL2973247 0.57
SCHEMBL558874 0.57 KDM4E (0.36) KDM4EMEN1ALOX15KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0796875-B1 Process for the preparation of crystalline vinylaromatic polymers with a predominant syndiotactic structure ENICHEM SPA (IT) 2000-03-29 EP disclosed
US-5721327-A Process for the preparation of crystalline vinylaromatic polymers with a predominant syndiotactic structure ENICHEM S.P.A. (IT) 1998-02-24 US disclosed
EP-0796875-A2 Process for the preparation of crystalline vinylaromatic polymers with a predominant syndiotactic structure ENICHEM S.p.A. (IT) 1997-09-24 EP disclosed