SCHEMBL558874

SCHEMBL558874

Cc1ccc2c(c1C)C(C)C(C)C(C)C2C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HTR2C P28335 2/20 0.33
TRPA1 O75762 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9551788 0.77 HTR2C (0.49) KDM4EMEN1KMT2AHSD17B10HTR2C
SCHEMBL15412523 0.66 BCL2L1 (0.37)
SCHEMBL18672402 0.65 KDM4E (0.31) KDM4EMEN1ALOX15KMT2AHSD17B10
SCHEMBL37955 0.61 TSHR (0.45) KDM4ETRPA1ATM
SCHEMBL5494672 0.61 TSHR (0.45) KDM4ETRPA1ATM
SCHEMBL1574024 0.61 GPR3 (0.36) KDM4EMEN1ALOX15KMT2AHSD17B10
SCHEMBL3407651 0.60 CYP1A2 (0.36) HTR2CTRPA1
SCHEMBL5181689 0.58 TSHR (0.43) KDM4ETRPA1ATM
SCHEMBL10346182 0.58 TSHR (0.43) KDM4ETRPA1ATM
SCHEMBL571577 0.58 TSHR (0.43) KDM4ETRPA1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109517175-A LED encapsulation high-quality phenyl vinyl MTQ silicone resin and preparation method 湖北新四海化工股份有限公司 2019-03-26 CN claimed
CN-108455563-A A kind of preparation method of Nitrogen-rich porous carbon microballoon 天津工业大学 2018-08-28 CN claimed
EP-0386900-A2 Deodorant compositions containing specific piroctone salts and perfumes THE PROCTER & GAMBLE COMPANY (US) 1990-09-12 EP claimed
EP-0380288-A1 Process for preparing 1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphtalene Union Camp Corporation (US) 1990-08-01 EP claimed
US-4906454-A Deodorant compositions containing specific piroctone salts and perfumes THE PROCTER & GAMBLE COMPANY (US) 1990-03-06 US claimed
WO-2024086550-A2 AEROSOL PERSONAL CARE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2024-04-25 WO disclosed
US-20240122820-A1 Aerosol Personal Care Products THE PROCTER & GAMBLE COMPANY 2024-04-18 US disclosed
US-11827443-B2 Aerosol foam dispenser THE PROCTER & GAMBLE COMPANY (US) 2023-11-28 US disclosed
US-20220354758-A1 FOAM COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2022-11-10 US disclosed
WO-2022235542-A1 FOAM COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2022-11-10 WO disclosed
CN-109517175-A LED encapsulation high-quality phenyl vinyl MTQ silicone resin and preparation method 湖北新四海化工股份有限公司 2019-03-26 CN disclosed
CN-108455563-A A kind of preparation method of Nitrogen-rich porous carbon microballoon 天津工业大学 2018-08-28 CN disclosed
US-4877913-A Process for preparing polyalkyl tetrahydronaphthalenes UNION CAMP CORPORATION (US) 1989-10-31 US disclosed
US-4877912-A Process for preparing 1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene UNION CAMP CORPORATION (US) 1989-10-31 US disclosed
US-4877915-A Process for preparing polyalkyl tetrahydronaphthalenes UNION CAMP CORPORATION (US) 1989-10-31 US disclosed
US-4877911-A Process for preparing polyalkyl tetrahydronaphthalenes UNION CAMP CORPORATION (US) 1989-10-31 US disclosed
US-4877916-A Process for preparing polyalkyl tetrahydronaphthalenes UNION CAMP CORPORATION (US) 1989-10-31 US disclosed
US-4877914-A CATALYTIC CYCLIZATION, ALKYLATION UNION CAMP CORPORATION (US) 1989-10-31 US disclosed
US-4877910-A Process for preparing polyalkyl tetrahydronaphthalenes UNION CAMP CORPORATION (US) 1989-10-31 US disclosed
US-4284818-A Process for preparing hexamethyltetrahydronaphthalenes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220354758-A1 FOAM COMPOSITIONS DSG1, DAGLA, DEK KDM4E 3413/4885MEN1 3732/4885ALOX15 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.