Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13677140 | 0.70 | — | — | |
| SCHEMBL8324725 | 0.68 | MAOA (0.43) | — | |
| SCHEMBL15222058 | 0.68 | MAOA (0.43) | — | |
| SCHEMBL8030397 | 0.68 | MAOA (0.43) | — | |
| SCHEMBL15222057 | 0.62 | SIGMAR1 (0.38) | — | |
| SCHEMBL5549793 | 0.62 | MAOA (0.50) | CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7506644 | 0.61 | MAPT (0.39) | — | |
| SCHEMBL3308482 | 0.60 | DRD2 (0.35) | — | |
| SCHEMBL25339816 | 0.60 | DRD1 (0.48) | — | |
| SCHEMBL19398830 | 0.60 | HRH3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |