Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.46 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006388 | 0.90 | RAF1 (0.44) | RAF1STK39RIPK1P2RX4PDK1 | |
| SCHEMBL8019561 | 0.82 | CYP3A4 (0.42) | RAF1PDK1PDK2PDK3PDK4 | |
| SCHEMBL8016868 | 0.80 | AR (0.52) | AR | |
| SCHEMBL8024928 | 0.78 | AR (0.48) | ARCDK8GRM4 | |
| SCHEMBL8018148 | 0.74 | AR (0.51) | ARRIPK1PDK1PDK2PDK3 | |
| SCHEMBL8005970 | 0.71 | KCNJ5 (0.55) | ARKCNJ5KCNJ3 | |
| SCHEMBL8024028 | 0.71 | AR (0.57) | ARRIPK1KCNJ5KCNJ3 | |
| SCHEMBL8015251 | 0.71 | AR (0.46) | ARCDK8RIPK1 | |
| SCHEMBL8021637 | 0.70 | RORC (0.40) | AR | |
| SCHEMBL9891509 | 0.70 | AR (0.63) | ARCDK8GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097995-A1 | NOVEL PHENYL-SUBSTITUTED IMIDAZOLIDINES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |