Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 4/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8025626 | 1.00 | EPHX1 (0.40) | EPHX1KIF11DPEP1GRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8041572 | 0.90 | EPHX1 (0.43) | EPHX1KIF11CCR2POLBRAB9A | |
| Cyclohexylamine SCHEMBL8041569 | 0.90 | EPHX1 (0.43) | EPHX1KIF11CCR2POLBRAB9A | |
| Cyclohexylamine SCHEMBL8039213 | 0.88 | GRIK1 (0.45) | EPHX1KIF11DPEP1GRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8039210 | 0.88 | GRIK1 (0.45) | EPHX1KIF11DPEP1GRIK1GRIK2 | |
| Lysine SCHEMBL8035212 | 0.88 | GSR (0.42) | EPHX1KIF11DPEP1GRIK1GRIK2 | |
| Lysine SCHEMBL8035214 | 0.88 | GSR (0.42) | EPHX1KIF11DPEP1GRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8041263 | 0.87 | EPHX1 (0.38) | EPHX1DPEP1CCR2TACR1POLB | |
| Cyclohexylamine SCHEMBL7792374 | 0.83 | EPHX1 (0.36) | EPHX1POLBRAB9ARPS6KA3JAK3 | |
| Cycloheptanamine SCHEMBL7801780 | 0.83 | EPHX1 (0.36) | EPHX1POLBRAB9ARPS6KA3JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |