Cyclohexylamine

Cyclohexylamine

SCHEMBL8041569

NC1CCCCC1.NC[C@H](N)C(=O)O.O=Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 4/20 0.43
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
KIF11 P52732 4/20 0.41
SLC1A3 P43003 3/20 0.40
SLC1A2 P43004 3/20 0.40
SLC1A1 P43005 3/20 0.40
GALR3 O60755 1/20 0.39
CCR2 P41597 1/20 0.39
EPHX2 P34913 1/20 0.38
DPP4 P27487 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
DPP7 Q9UHL4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL8041572 1.00 EPHX1 (0.43) EPHX1POLBRAB9AKIF11SLC1A3
Cyclohexylamine SCHEMBL8025626 0.90 EPHX1 (0.40) EPHX1POLBRAB9AKIF11SLC1A3
Cyclohexylamine SCHEMBL8025629 0.90 EPHX1 (0.40) EPHX1POLBRAB9AKIF11SLC1A3
Lysine SCHEMBL8035654 0.89 EPHX1 (0.40) EPHX1POLBRAB9AKIF11SLC1A3
Lysine SCHEMBL8035651 0.89 EPHX1 (0.40) EPHX1POLBRAB9AKIF11SLC1A3
Cyclohexylamine SCHEMBL8035100 0.89 POLB (0.42) EPHX1POLBRAB9AGALR3CCR2
Cyclohexylamine SCHEMBL8039213 0.88 GRIK1 (0.45) EPHX1KIF11SLC1A3SLC1A2SLC1A1
Cyclohexylamine SCHEMBL8039210 0.88 GRIK1 (0.45) EPHX1KIF11SLC1A3SLC1A2SLC1A1
Cyclohexylamine SCHEMBL8041254 0.85 TP53 (0.41) RAB9AKIF11SLC1A1DPP4DPP8
Cyclohexylamine SCHEMBL8041252 0.85 TP53 (0.41) RAB9AKIF11SLC1A1DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127381-A A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY LION BIOSCIENCE AG (DE) 2000-10-03 US disclosed