Cyclohexylamine

Cyclohexylamine

SCHEMBL8039210

NC1CCCCC1.NC[C@H](N)C(=O)O.O=Cc1ccc(C(F)(F)F)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.45
GRIK2 Q13002 1/20 0.45
DPEP1 P16444 1/20 0.44
KIF11 P52732 5/20 0.40
GRM8 O00222 1/20 0.37
GRM4 Q14833 1/20 0.37
DPP4 P27487 1/20 0.36
FAP Q12884 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
GRB2 P62993 1/20 0.35
XBP1 P17861 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
EPHX1 P07099 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MCHR1 Q99705 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL8039213 1.00 GRIK1 (0.45) GRIK1GRIK2DPEP1KIF11GRM8
Cyclohexylamine SCHEMBL8025626 0.88 EPHX1 (0.40) GRIK1GRIK2DPEP1KIF11SLC1A3
Cyclohexylamine SCHEMBL8025629 0.88 EPHX1 (0.40) GRIK1GRIK2DPEP1KIF11SLC1A3
Lysine SCHEMBL8039030 0.88 GSR (0.42) GRIK1GRIK2DPEP1KIF11GRM8
Cyclohexylamine SCHEMBL8041569 0.88 EPHX1 (0.43) KIF11DPP4DPP8DPP9DPP7
Cyclohexylamine SCHEMBL8041572 0.88 EPHX1 (0.43) KIF11DPP4DPP8DPP9DPP7
Cyclohexylamine SCHEMBL8037697 0.87 GRIK1 (0.41) GRIK1GRIK2DPEP1KIF11
Cyclohexylamine SCHEMBL8037696 0.87 GRIK1 (0.41) GRIK1GRIK2DPEP1KIF11
Cyclohexylamine SCHEMBL8025513 0.87 DPEP1 (0.43) GRIK1GRIK2DPEP1XBP1PTGDR2
4-Hydroxybenzaldehyde SCHEMBL8037281 0.85 ALDH5A1 (0.41) GRIK1GRIK2KIF11SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127381-A A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY LION BIOSCIENCE AG (DE) 2000-10-03 US disclosed