Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL8035799 | 0.92 | TAAR1 (0.44) | TAAR1MAOBNPC1POLBRAB9A | |
| 4-Methylbenzoic Acid SCHEMBL7802556 | 0.90 | SRD5A2 (0.46) | NR4A2SRD5A2 | |
| SCHEMBL8035858 | 0.90 | MAOB (0.46) | TAAR1MAOBNPC1RAB9ATDP1 | |
| 4-Methylbenzoic Acid SCHEMBL8035699 | 0.90 | MAOB (0.43) | MAOBPOLBSMN1; SMN2CYP1A1CYP1B1 | |
| 4-Methylbenzoic Acid SCHEMBL7792499 | 0.89 | TAAR1 (0.47) | TAAR1MAOBTDP1ALDH1A1KDM4E | |
| 4-Methylbenzoic Acid SCHEMBL7798106 | 0.89 | SRD5A2 (0.41) | TAAR1SMN1; SMN2L3MBTL1CYP1A1CYP1B1 | |
| 4-Methylbenzoic Acid SCHEMBL7792063 | 0.89 | RXRA (0.42) | TAAR1NPC1RAB9ASMN1; SMN2MAPT | |
| 4-Methylbenzoic Acid SCHEMBL7798453 | 0.88 | KDM4E (0.46) | TAAR1NPC1RAB9ASMN1; SMN2MAPT | |
| 4-Methylbenzoic Acid SCHEMBL7792518 | 0.88 | SCN5A (0.40) | TAAR1NPC1POLBRAB9AMAPK1 | |
| SCHEMBL7801502 | 0.87 | TAAR1 (0.55) | TAAR1MAOBNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |