Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL8035799 | 0.94 | TAAR1 (0.44) | MAOBNPC1RAB9ATAAR1LPAR1 | |
| SCHEMBL7798437 | 0.91 | SRD5A2 (0.47) | MAOBRXRARXRBRXRGTRIM24 | |
| SCHEMBL8035116 | 0.91 | PTGES (0.48) | MAOBRXRARXRBRXRGTAAR1 | |
| SCHEMBL7802496 | 0.91 | RXRA (0.46) | MAOBRXRARXRBRXRGNPC1 | |
| 4-Methylbenzoic Acid SCHEMBL8025639 | 0.90 | TAAR1 (0.42) | MAOBRXRARXRBRXRGNPC1 | |
| Phenethylamine SCHEMBL7799179 | 0.90 | RXRA (0.52) | MAOBRXRARXRBRXRGNPC1 | |
| SCHEMBL7798405 | 0.89 | SMN1; SMN2 (0.46) | RXRARXRBRXRGKDM4ETDP1 | |
| Tyramine SCHEMBL8035895 | 0.88 | RXRA (0.48) | MAOBRXRARXRBRXRGTAAR1 | |
| SCHEMBL7802656 | 0.87 | RXRA (0.47) | MAOBRXRARXRBRXRGRAB9A | |
| Benzoic Acid SCHEMBL7798612 | 0.86 | MAOB (0.51) | MAOBNPC1RAB9ATAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |