Glycerin

Glycerin

SCHEMBL8025707

CCC(C)=O.OCC(O)CO.OCC(O)CO

nearest known ligand 0.59

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
TDP1 Q9NUW8 4/20 0.59
LMNA P02545 3/20 0.53
KDM4E B2RXH2 1/20 0.36
DUSP3 P51452 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
THRB P10828 1/20 0.36
FFAR3 O14843 1/20 0.35
OR51E2 Q9H255 1/20 0.35
TRPA1 O75762 1/20 0.33
USP2 O75604 1/20 0.32
SLC22A16 Q86VW1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL1513106 1.00 ALDH1A1 (0.59) ALDH1A1TDP1LMNAKDM4EDUSP3
Glycerin SCHEMBL1936682 0.85 ALDH1A1 (0.56) ALDH1A1TDP1LMNAKDM4EDUSP3
Glycerin SCHEMBL1831824 0.84 LMNA (0.64) ALDH1A1TDP1LMNAKDM4EDUSP3
Glycerin SCHEMBL93722 0.84 LMNA (0.64) ALDH1A1TDP1LMNAKDM4EDUSP3
Glycerin SCHEMBL4554867 0.84 LMNA (0.64) ALDH1A1TDP1LMNAKDM4EDUSP3
Glycerin SCHEMBL28671296 0.84 ALDH1A1 (0.42) ALDH1A1TDP1LMNAKDM4EDUSP3
Glycerin SCHEMBL3201399 0.83 FFAR3 (0.53) ALDH1A1TDP1LMNAKDM4EDUSP3
Glycerin SCHEMBL1685705 0.83 FFAR3 (0.53) ALDH1A1TDP1LMNAKDM4EDUSP3
Glycerin SCHEMBL22720645 0.83 FFAR3 (0.53) ALDH1A1TDP1LMNAKDM4EDUSP3
Glycerin SCHEMBL1685702 0.83 FFAR3 (0.53) ALDH1A1TDP1LMNAKDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6096692-A CYLIC KETALS AND ACDTALS HAVING HEAT AND OXIDATION RESISTANCE, ARE FREE FROM CARBOXYLIC ACIDS FORMING DUE TO HYDROLYSIS, LOW IN HYGROSCOPICITY, INEXPENSIVE, GOOD INSULATION AND COMPATIBLE WITH HYDROFLUOROCARBONS; WORKING FLUID REFRIGERANTS KAO CORPORATION (JP) 2000-08-01 US disclosed