Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746938 | 0.86 | ERN1 (0.45) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL2201698 | 0.82 | ALDH1A1 (0.42) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL3698426 | 0.79 | POLB (0.46) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL11804268 | 0.79 | ALDH1A1 (0.42) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL16908453 | 0.78 | ALDH1A1 (0.35) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL16908455 | 0.78 | PAX8 (0.36) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL1088157 | 0.76 | KDM4E (0.42) | TDP1ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL10186709 | 0.75 | ERN1 (0.55) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL8490846 | 0.75 | CYP3A4 (0.37) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL9310776 | 0.75 | SLC2A1 (0.43) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973714-A2 | PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998030528-A2 | PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |