Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030138 | 0.78 | ITK (0.41) | ACSL1ALDH1A1ITK | |
| SCHEMBL8136672 | 0.78 | NPC1 (0.43) | NPC1KDM4EHTTLMNAHSD17B10 | |
| SCHEMBL8026022 | 0.77 | MAPT (0.43) | NPC1KDM4EHTTLMNAHSD17B10 | |
| SCHEMBL8030134 | 0.75 | KMT2A (0.44) | NPC1KDM4ELMNAHSD17B10ACSL1 | |
| SCHEMBL8029591 | 0.75 | ALDH1A1 (0.44) | NPC1KDM4ELMNAHSD17B10ACSL1 | |
| SCHEMBL8029893 | 0.74 | F2 (0.46) | LMNAHSD17B10ACSL1USP2SMN1; SMN2 | |
| SCHEMBL8027045 | 0.73 | F2 (0.45) | NPC1KDM4EHTTLMNAACSL1 | |
| SCHEMBL8017278 | 0.72 | ITK (0.51) | NPC1KDM4EACSL1ITK | |
| SCHEMBL8027395 | 0.72 | F2 (0.52) | LMNASMN1; SMN2 | |
| SCHEMBL8029593 | 0.72 | ACSL1 (0.42) | NPC1KDM4ELMNAHSD17B10ACSL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |