Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026022 | 0.78 | MAPT (0.43) | KMT2AALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL8029591 | 0.76 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL8030127 | 0.75 | NPC1 (0.42) | ALDH1A1KDM4ELMNAHSD17B10NPC1 | |
| SCHEMBL8136672 | 0.73 | NPC1 (0.43) | ALDH1A1KDM4ELMNAHSD17B10NPC1 | |
| SCHEMBL8030145 | 0.73 | ACSL1 (0.41) | ACSL1 | |
| SCHEMBL8016515 | 0.72 | ITK (0.44) | KMT2AKDM4ELMNAHSD17B10ACSL1 | |
| SCHEMBL8017278 | 0.71 | ITK (0.51) | KDM4ENPC1ACSL1 | |
| SCHEMBL8029893 | 0.71 | F2 (0.46) | LMNAHSD17B10SMN1; SMN2ACSL1 | |
| SCHEMBL8027045 | 0.71 | F2 (0.45) | ALDH1A1KDM4ELMNANPC1SMN1; SMN2 | |
| SCHEMBL8029593 | 0.71 | ACSL1 (0.42) | KMT2AMEN1KDM4ELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |