Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.39 |
| ▸ | CA1 | P00915 | 7/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | CA6 | P23280 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662574 | 0.90 | HTR1A (0.37) | CA2CA1CA9CA6CA12 | |
| SCHEMBL10664679 | 0.76 | CA2 (0.44) | CA2CA1CA9CA6CA12 | |
| SCHEMBL10689475 | 0.72 | CA2 (0.34) | CA2CA1CA9CA6CA12 | |
| SCHEMBL10816016 | 0.71 | BCL2L1 (0.42) | CA2CA1CA6CA12CA4 | |
| SCHEMBL10816476 | 0.71 | KDM4E (0.41) | LMNA | |
| SCHEMBL13972198 | 0.71 | KDM1A (0.30) | — | |
| SCHEMBL10671465 | 0.69 | CA2 (0.40) | CA2CA1CA9CA6CA12 | |
| SCHEMBL10690337 | 0.68 | CA2 (0.33) | CA2CA1CA9CA6CA12 | |
| SCHEMBL10501346 | 0.68 | CA2 (0.36) | CA2CA1CA9CA6CA12 | |
| SCHEMBL10785372 | 0.68 | CA2 (0.36) | CA2CA1CA9CA6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063202-A2 | BENZO[b] THIOPHENE SULFONAMIDE-1, 1-DIOXIDE DERIVATIVES AND THEIR USE AS ANTINEOPLASTIC AGENTS | UNIVERSIDAD PUBLICA DE NAVARRA (ES) | 2000-10-26 | — | — | WO | disclosed |
| US-4695310-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-22 | — | — | US | disclosed |
| US-4612035-A | Herbicidal N-[(4-bromo-6-methoxypyrimidin-2-yl)aminocarbonyl]-2,3-dihydro-(2-methyl)benzo[b]thiophene-7-sulfonamides, 1,1-dioxide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-16 | — | — | US | disclosed |
| US-4589909-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| US-4514211-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-30 | — | — | US | disclosed |