SCHEMBL10690337

SCHEMBL10690337

CC(C)N1Cc2cccc(S(N)(=O)=O)c2S1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.33
CA1 P00915 5/20 0.33
CA9 Q16790 4/20 0.33
STAT3 P40763 1/20 0.33
CDK2 P24941 1/20 0.33
CA6 P23280 3/20 0.33
CA4 P22748 2/20 0.33
CA12 O43570 2/20 0.33
CA5A P35218 2/20 0.33
CA7 P43166 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
CYP2C9 P11712 1/20 0.33
CA14 Q9ULX7 1/20 0.33
MAPK1 P28482 1/20 0.30
PTGES2 Q9H7Z7 2/20 0.30
PNMT P11086 1/20 0.30
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10626158 0.80 CA2 (0.36) CA2CA1CA9STAT3CDK2
SCHEMBL10686568 0.75 LMNA (0.34) CA2CA1CA9STAT3CDK2
SCHEMBL10689475 0.72 CA2 (0.34) CA2CA1CA9STAT3CDK2
SCHEMBL8026041 0.68 CA2 (0.39) CA2CA1CA9STAT3CDK2
SCHEMBL10662574 0.66 HTR1A (0.37) CA2CA1CA9STAT3CDK2
SCHEMBL9663854 0.65 CA2 (0.33) CA2CA1CA9STAT3CDK2
SCHEMBL10501346 0.65 CA2 (0.36) CA2CA1CA9STAT3CDK2
SCHEMBL10785372 0.65 CA2 (0.36) CA2CA1CA9STAT3CDK2
SCHEMBL10808580 0.63 CA2 (0.52) CA2CA1CA9STAT3CDK2
SCHEMBL10671465 0.63 CA2 (0.40) CA2CA1CA9STAT3CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4741761-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-03 US disclosed
US-4620870-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-11-04 US disclosed
US-4586950-A HERBICIDES E. I. DU PONT DE NEMOURS & COMPANY (US) 1986-05-06 US disclosed