Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595549 | 0.95 | MAPK1 (0.42) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8887768 | 0.92 | MAPK1 (0.46) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8024400 | 0.84 | MAPK1 (0.45) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8026050 | 0.80 | MAPK1 (0.43) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL7803498 | 0.80 | MAPK1 (0.40) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8024403 | 0.74 | LMNA (0.57) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8887045 | 0.74 | LMNA (0.57) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL15570409 | 0.73 | CA1 (0.46) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL13433889 | 0.73 | MAPK1 (0.55) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL18633373 | 0.73 | LMNA (0.68) | MAPK1ATMLMNAALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700825-A | USED TO KILL HYPOXIC TUMOR CELLS | FLORIDA STATE UNIVERSITY (US) | 1997-12-23 | — | — | US | disclosed |