Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.48 |
| ▸ | PPARA | Q07869 | 12/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020434 | 0.92 | PPARG (0.47) | PPARGPPARANPC1RAB9AL3MBTL1 | |
| SCHEMBL8021998 | 0.85 | PPARG (0.48) | PPARGPPARANPC1RAB9AL3MBTL1 | |
| SCHEMBL8500995 | 0.84 | HIF1A (0.43) | NPC1RAB9AL3MBTL1SMN1; SMN2HIF1A | |
| SCHEMBL8020919 | 0.81 | MAPT (0.38) | NPC1RAB9AL3MBTL1SMN1; SMN2HIF1A | |
| SCHEMBL8026917 | 0.80 | KMT2A (0.41) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7770720 | 0.78 | L3MBTL1 (0.44) | NPC1RAB9AL3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL8026087 | 0.77 | PPARG (0.50) | PPARGPPARANPC1RAB9AL3MBTL1 | |
| SCHEMBL8500992 | 0.76 | HIF1A (0.42) | NPC1RAB9ASMN1; SMN2HIF1A | |
| SCHEMBL8500990 | 0.76 | HIF1A (0.42) | NPC1RAB9ASMN1; SMN2HIF1A | |
| SCHEMBL8026513 | 0.74 | ALDH1A1 (0.39) | NPC1RAB9AL3MBTL1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975587-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998043949-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-08 | — | — | WO | disclosed |