Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 18/20 | 0.40 |
| ▸ | MMP1 | P03956 | 16/20 | 0.40 |
| ▸ | MMP2 | P08253 | 13/20 | 0.40 |
| ▸ | MMP9 | P14780 | 10/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.40 |
| ▸ | MMP7 | P09237 | 4/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | MMP20 | O60882 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP10 | P09238 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP15 | P51511 | 1/20 | 0.40 |
| ▸ | MMP16 | P51512 | 1/20 | 0.40 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.40 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | MMP24 | Q9Y5R2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513209 | 0.90 | MMP1 (0.44) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL9010568 | 0.81 | MMP1 (0.35) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL8422654 | 0.80 | MMP1 (0.34) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6435917 | 0.79 | POLB (0.38) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL8777490 | 0.79 | POLB (0.38) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL8028148 | 0.78 | MMP1 (0.52) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL9010562 | 0.78 | ADAM17 (0.34) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL8198199 | 0.78 | ADAM17 (0.34) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL8424797 | 0.77 | MMP1 (0.32) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL8189731 | 0.77 | MMP1 (0.32) | MMP3MMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861226-B1 | SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES | BRITISH BIOTECH PHARM (GB) | 2000-02-23 | — | — | EP | disclosed |
| US-5986132-A | Synthesis of carboxylic acid derivatives | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 1999-11-16 | — | — | US | disclosed |
| EP-0861226-A1 | SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997019050-A1 | SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |