Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | MMP3 | P08254 | 3/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373809 | 0.92 | MMP1 (0.56) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL7406988 | 0.79 | MMP1 (0.43) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL8396770 | 0.78 | MMP1 (0.54) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL8026129 | 0.78 | MMP3 (0.40) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL7410121 | 0.77 | MMP2 (0.47) | MMP1MMP3MMP2POLBLMNA | |
| SCHEMBL8397891 | 0.75 | MMP1 (0.47) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL7404962 | 0.75 | MMP1 (0.47) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL7370348 | 0.75 | MMP2 (0.46) | MMP1MMP3MMP9MMP2FFAR2 | |
| SCHEMBL7366585 | 0.74 | MMP1 (0.59) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL7411892 | 0.74 | MMP2 (0.44) | MMP1MMP3MMP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861226-B1 | SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES | BRITISH BIOTECH PHARM (GB) | 2000-02-23 | — | — | EP | disclosed |
| US-5986132-A | Synthesis of carboxylic acid derivatives | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 1999-11-16 | — | — | US | disclosed |