Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA4 | P22748 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21906404 | 0.93 | KDM4E (0.70) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL29850315 | 0.93 | KDM4E (0.70) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL20680057 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL17189587 | 0.86 | KDM4E (0.75) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL22680245 | 0.83 | ALDH1A1 (0.62) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL1507161 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL52405 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL29366129 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL5949863 | 0.77 | POLB (0.42) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL30366469 | 0.77 | POLB (0.42) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973714-A2 | PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 2000-01-26 | — | — | EP | disclosed |
| EP-0937021-A1 | PRODUCTION OF NABUMETONE OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1999-08-25 | — | — | EP | disclosed |
| US-5907069-A | METHYLATION OF 6-BROMO-2-NAPHTHOL WITH METHYL BROMIDE OR METHYL CHLORIDE AND RECOVERING NABUMETONE | ALBEMARLE CORPORATION (US) | 1999-05-25 | — | — | US | disclosed |
| US-5792886-A | METHYLATION OF 6-BROMO-2-NAPHTHOL WITH METHYL BROMIDE TO 2-BROMO-6-METHOXYNAPHTHALENE; FORMING GRIGNARD; REACTING WITH A LOWER ALKYL 2-BROMOPROPIONATE | ALBEMARLE CORPORATION (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1998030528-A2 | PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
| WO-1998017616-A1 | PRODUCTION OF NABUMETONE OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1998-04-30 | — | — | WO | disclosed |