Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13687845 | 0.79 | PTGDR2 (0.42) | CA1CA2HTR2APTGDR2 | |
| SCHEMBL3790291 | 0.77 | ENPP2 (0.40) | ENPP2CA1CA2 | |
| SCHEMBL851880 | 0.76 | ENPP2 (0.36) | ENPP2CA1CA2TUBB4ATUBB | |
| SCHEMBL23114 | 0.75 | ENPP2 (0.52) | ENPP2CA1CA2TUBB4ATUBB | |
| SCHEMBL16957840 | 0.74 | ACHE (0.54) | HTR2CHTR2APTGDR2KMT2A | |
| SCHEMBL16950302 | 0.74 | HTR2C (0.41) | CA1CA2HTR2CHTR2APTGDR2 | |
| SCHEMBL16957839 | 0.73 | HTR2C (0.43) | CA2HTR2CHTR2APTGDR2MEN1 | |
| SCHEMBL21231846 | 0.73 | SLC6A2 (0.54) | HTR2CHTR2APTGDR2 | |
| SCHEMBL3790241 | 0.73 | ENPP2 (0.39) | ENPP2CA1CA2 | |
| SCHEMBL7938441 | 0.73 | KDM4E (0.46) | HTR2CHTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089027-A1 | PHOSPHODIESTERASE INHIBITORS | GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICE, NATIONAL INSTITUTES OF HEALTH (US) | 2009-07-16 | — | — | WO | disclosed |