Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321067 | 0.79 | POLB (0.47) | PTGS2AOC3MEN1KMT2AMAPK1 | |
| SCHEMBL3641441 | 0.79 | HTR2A (0.59) | PTGS2AOC3HTR2AHTR2CHTR2B | |
| SCHEMBL12933661 | 0.78 | PTGS2 (0.59) | PTGS2AOC3HTR2AHTR2CHTR2B | |
| SCHEMBL7447368 | 0.77 | ACHE (0.46) | PTGS2AOC3CYP3A4CYP2D6THPO | |
| SCHEMBL6670969 | 0.77 | KDM4E (0.45) | PTGS2AOC3MEN1KMT2AALDH1A1 | |
| SCHEMBL8326095 | 0.76 | KDM4E (0.44) | PTGS2AOC3MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7645327 | 0.76 | KDM4E (0.44) | PTGS2AOC3MEN1PMP22KMT2A | |
| SCHEMBL6716017 | 0.76 | L3MBTL1 (0.45) | PTGS2AOC3MEN1KMT2AALDH1A1 | |
| SCHEMBL16884174 | 0.76 | CYP3A4 (0.45) | PTGS2AOC3CYP3A4CYP2D6THPO | |
| SCHEMBL7338634 | 0.75 | AOC3 (0.62) | PTGS2AOC3CYP3A4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816324-B1 | Subsituted benzyl derivatives of polyalkylene-polyamines and their use in cosmetic and pharmaceutical compositions | OREAL (FR) | 2000-02-16 | — | — | EP | claimed |
| EP-0816324-A1 | Subsituted benzyl derivatives of polyalkylene-polyamines and their use in cosmetic and pharmaceutical compositions | L'OREAL (FR) | 1998-01-07 | — | — | EP | claimed |
| EP-0816324-B1 | Subsituted benzyl derivatives of polyalkylene-polyamines and their use in cosmetic and pharmaceutical compositions | OREAL (FR) | 2000-02-16 | — | — | EP | disclosed |
| US-5910513-A | PROTECTING THE BODY AGAINST OXIDATIVE STRESS SUCH AS NEURODEGENERATIVE DISEASES, PARKINSON'S DISEASE, CHRONIC INFLAMMATORY CONDITIONS, REINFUSION ISCHAEMIA SYNDROME, THE TOXICITY OF CERTAIN DRUGS SUCH AS CERTAIN XENOBIOTICS | L'OREAL (FR) | 1999-06-08 | — | — | US | disclosed |
| EP-0816324-A1 | Subsituted benzyl derivatives of polyalkylene-polyamines and their use in cosmetic and pharmaceutical compositions | L'OREAL (FR) | 1998-01-07 | — | — | EP | disclosed |