Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038096 | 0.82 | CA2 (0.38) | HRH3HRH4FFAR1FFAR4SLC6A2 | |
| SCHEMBL7797531 | 0.81 | GRM2 (0.45) | HRH3HRH4 | |
| SCHEMBL8425149 | 0.81 | MAPKAPK2 (0.37) | HRH3HRH4FFAR1FFAR4NPC1 | |
| SCHEMBL7297674 | 0.81 | HRH3 (0.38) | HRH3HRH4NPC1RAB9ALMNA | |
| SCHEMBL8280054 | 0.81 | HRH3 (0.38) | HRH3HRH4NPC1RAB9ALMNA | |
| SCHEMBL7297669 | 0.81 | HRH3 (0.38) | HRH3HRH4NPC1RAB9ALMNA | |
| SCHEMBL7788802 | 0.80 | FFAR4 (0.51) | FFAR1FFAR4 | |
| SCHEMBL8036686 | 0.78 | HRH3 (0.60) | HRH3FFAR1FFAR4LMNAKDM4E | |
| SCHEMBL8282287 | 0.78 | HRH3 (0.43) | HRH3HRH4NPC1RAB9ALMNA | |
| SCHEMBL8026169 | 0.77 | HRH3 (0.47) | HRH3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000076990-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-12-21 | — | — | WO | disclosed |