Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117533 | 0.88 | HRH3 (0.63) | HRH3GABRA1GABRB2MTNR1ALMNA | |
| Methylamine SCHEMBL10700886 | 0.87 | HRH3 (0.59) | HRH3GABRA1GABRB2MTNR1AGLS | |
| SCHEMBL5505186 | 0.81 | HRH3 (0.55) | HRH3GABRA1GABRB2DRD2DRD3 | |
| SCHEMBL13802286 | 0.81 | FFAR1 (0.56) | HRH3GABRA1GABRB2MTNR1AGLS | |
| SCHEMBL17761389 | 0.79 | HRH3 (0.56) | HRH3GABRA1GABRB2MTNR1ALMNA | |
| SCHEMBL8026316 | 0.78 | HRH3 (0.38) | HRH3LMNAFFAR1FFAR4KDM4E | |
| SCHEMBL10256487 | 0.78 | HRH3 (0.59) | HRH3GABRA1GABRB2MTNR1ALMNA | |
| SCHEMBL9628115 | 0.77 | HRH3 (0.57) | HRH3GABRA1GABRB2MTNR1ALMNA | |
| SCHEMBL8036693 | 0.77 | FFAR1 (0.52) | HRH3MTNR1ADRD2DRD3FFAR1 | |
| SCHEMBL8038096 | 0.77 | CA2 (0.38) | HRH3GLSFFAR1FFAR4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000076990-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-12-21 | — | — | WO | disclosed |