Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425199 | 0.86 | MAPKAPK2 (0.36) | MAPKAPK2FFAR1FFAR4 | |
| SCHEMBL8026316 | 0.81 | HRH3 (0.38) | MAPKAPK2HRH3HRH4NPC1LMNA | |
| SCHEMBL8425913 | 0.78 | HRH3 (0.43) | HRH3 | |
| SCHEMBL8426347 | 0.77 | PNMT (0.38) | NPC1LMNARAB9A | |
| SCHEMBL7797531 | 0.77 | GRM2 (0.45) | HRH3HRH4 | |
| SCHEMBL7297669 | 0.76 | HRH3 (0.38) | MAPKAPK2HRH3HRH4NPC1LMNA | |
| SCHEMBL7297674 | 0.76 | HRH3 (0.38) | MAPKAPK2HRH3HRH4NPC1LMNA | |
| SCHEMBL8280054 | 0.76 | HRH3 (0.38) | MAPKAPK2HRH3HRH4NPC1LMNA | |
| SCHEMBL18143171 | 0.76 | MAPKAPK2 (0.30) | MAPKAPK2 | |
| SCHEMBL16851328 | 0.76 | MAPKAPK2 (0.30) | MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925662-A | OXIDASE INHIBITORS | SYNTHELABO (FR) | 1999-07-20 | — | — | US | disclosed |
| EP-0859776-A1 | COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017347-A1 | COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-05-15 | — | — | WO | disclosed |