SCHEMBL802655

SCHEMBL802655

Cc1ccc(CCC2CCC(C)CC2)c(Cl)c1F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CEL P19835 2/20 0.35
HTR2A P28223 3/20 0.32
HTR2C P28335 3/20 0.32
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24778739 0.94 CEL (0.39) CELHTR2AHTR2CHTR2B
SCHEMBL802762 0.88 CEL (0.35) CELHTR2AHTR2C
SCHEMBL30200 0.86 HTR2A (0.32) CELHTR2AHTR2C
SCHEMBL803107 0.86 HTR2A (0.32) CELHTR2AHTR2C
SCHEMBL14205127 0.85 SCN9A (0.34) CELHTR2AHTR2CHTR2B
SCHEMBL26167263 0.84 CEL (0.35) CELHTR2AHTR2C
SCHEMBL13235333 0.83 CEL (0.34) CELHTR2AHTR2C
SCHEMBL13111393 0.82 HTR2A (0.33) CELHTR2AHTR2C
SCHEMBL14205119 0.82 ALDH1A1 (0.36) HTR2AHTR2CHTR2B
SCHEMBL19985632 0.81 CTSL (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-11873438-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
WO-2023232753-A1 FERROELECTRIC SMECTIC LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-12-07 WO disclosed
US-20230383186-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-11-30 US disclosed
US-20230357637-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-11-09 US disclosed
US-11802243-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-31 US disclosed
US-20230323209-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-20230295510-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-09-21 US disclosed
US-20230295511-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-09-21 US disclosed
US-7807068-B2 reacting 4-halo-2,6-difluorophenol with protecting group, dehalogenating to form protected phenol ether group, reacting with boronic acid/ester, coupling in presence of catalyst, deblocking, etherifying, esterifying; for optical, electro-optical and electronic use, liquid-crystal media and displays MERCK PATENT GESELLSCHAFT (DE) 2010-10-05 US disclosed
US-20100243958-A1 Liquid Crystalline Medium KLASEN-MEMMER MELANIE 2010-09-30 US disclosed
US-7767280-B2 Liquid-crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-08-03 US disclosed
US-7731865-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2010-06-08 US disclosed
US-20100102275-A1 LIQUID-CRYSTALLINE MEDIUM KLASEN-MEMMER MELANIE 2010-04-29 US disclosed
US-20090324853-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-12-31 US disclosed
US-20090141215-A1 POLYMERIZABLE COMPOUNDS MERCK PATENT GESELLSCHAFT (DE) 2009-06-04 US disclosed
US-20090103011-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GESELLSCHAFT (DE) 2009-04-23 US disclosed
US-20080191167-A1 Liquid-crystalline medium MERCK PATENT GMBH 2008-08-14 US disclosed
US-20080090026-A1 Liquid-crystal display MERCK PATENT GMBH 2008-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090026-A1 Liquid-crystal display KLK3, LPXN, BPHL CEL 800/4885HTR2A 2557/4885HTR2C 1738/4885
US-20090141215-A1 POLYMERIZABLE COMPOUNDS VCL, LCP1, LPXN CEL 1232/4885HTR2A 4504/4885HTR2C 4018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.