Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROR1 | Q01973 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587345 | 0.82 | ALDH1A1 (0.44) | ROR1ALDH1A1KDM4ERAB9AMAPK1 | |
| SCHEMBL14285984 | 0.71 | ACHE (0.42) | ALDH1A1KDM4ERAB9AACHEMAPK1 | |
| SCHEMBL18288113 | 0.71 | ALDH1A1 (0.58) | ALDH1A1RAB9AACHEMAPK3MAPK1 | |
| SCHEMBL10291138 | 0.71 | FYN (0.40) | ROR1ALDH1A1KDM4EMAPK1CYP19A1 | |
| SCHEMBL9778921 | 0.70 | KDM4E (0.49) | ALDH1A1KDM4EMAPK1TSHR | |
| SCHEMBL10144993 | 0.70 | NPC1 (0.43) | ROR1ALDH1A1KDM4ERAB9AMAPK1 | |
| SCHEMBL19923130 | 0.69 | NPC1 (0.42) | ROR1RAB9ACYP19A1 | |
| SCHEMBL12191682 | 0.68 | ALDH1A1 (0.44) | ALDH1A1RAB9AACHEMAPK3MAPK1 | |
| SCHEMBL8303700 | 0.68 | ALDH1A1 (0.40) | ALDH1A1RAB9ACYP3A4CYP2D6TSHR | |
| SCHEMBL15068444 | 0.68 | CYP3A4 (0.39) | ALDH1A1KDM4ERAB9ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098287-A1 | PHENYL-PRENYL DERIVATIVES, OF MARINE AND SYNTHETIC ORIGIN, FOR THE TREATMENT OF COGNITIVE, NEURODEGENERATIVE OR NEURONAL DISEASES OR DISORDERS | NOSCIRA S.A. (ES) | 2009-08-13 | — | — | WO | disclosed |