Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | TACR3 | P29371 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630773 | 0.95 | TACR1 (0.38) | TACR1TACR2TACR3 | |
| Water SCHEMBL7749169 | 0.94 | TACR1 (0.37) | TACR1TACR2TACR3 | |
| SCHEMBL4631313 | 0.86 | ADRB2 (0.37) | TACR1TACR2 | |
| Water SCHEMBL7749198 | 0.85 | ADRB2 (0.38) | TACR1TACR2 | |
| SCHEMBL4631689 | 0.84 | TACR1 (0.35) | TACR1TACR2TACR3 | |
| Water SCHEMBL7744617 | 0.83 | TACR1 (0.34) | TACR1TACR2TACR3 | |
| SCHEMBL7764281 | 0.80 | CCR5 (0.46) | TACR1TACR2TACR3 | |
| SCHEMBL4631194 | 0.80 | TACR1 (0.38) | TACR1TACR2TACR3 | |
| SCHEMBL8456852 | 0.80 | TACR1 (0.33) | TACR1 | |
| SCHEMBL8991942 | 0.79 | TACR1 (0.53) | TACR1TACR2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011154-A | Substituted heterocyclic compounds, method of preparing them and pharmaceutical compositions in which they are present | SANOFI (FR) | 2000-01-04 | — | — | US | disclosed |
| EP-0915882-A1 | 1-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004561-A1 | 1-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |