Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630794 | 0.95 | HSD11B1 (0.34) | TACR1SIRT2SIRT1ADRB2FPR1 | |
| Hydrochloric Acid SCHEMBL7750338 | 0.94 | ADRB2 (0.34) | TACR1SIRT2SIRT1ADRB2FPR1 | |
| Water SCHEMBL7750307 | 0.94 | ADRB2 (0.34) | TACR1SIRT2SIRT1ADRB2FPR1 | |
| SCHEMBL4631689 | 0.85 | TACR1 (0.35) | TACR1SIRT2SIRT1CYP3A4ALDH1A1 | |
| Water SCHEMBL7744617 | 0.84 | TACR1 (0.34) | TACR1SIRT2SIRT1CYP3A4ALDH1A1 | |
| SCHEMBL4631313 | 0.84 | ADRB2 (0.37) | TACR1SIRT2SIRT1ADRB2FPR1 | |
| Water SCHEMBL7749198 | 0.83 | ADRB2 (0.38) | TACR1SIRT2SIRT1ADRB2FPR1 | |
| SCHEMBL8026646 | 0.80 | TACR1 (0.37) | TACR1 | |
| SCHEMBL4630804 | 0.79 | HSD11B1 (0.37) | TACR1SIRT2SIRT1ADRB2FPR1 | |
| SCHEMBL4631605 | 0.78 | TACR1 (0.34) | TACR1SIRT2SIRT1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915882-A1 | 1-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004561-A1 | 1-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |