Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027627 | 0.90 | CYP3A4 (0.38) | CYP3A4CYP2C9APPFFAR4HSP90AA1 | |
| SCHEMBL8026796 | 0.80 | CYP3A4 (0.38) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL8398345 | 0.77 | P2RY14 (0.33) | CYP3A4NOTUM | |
| SCHEMBL8398342 | 0.77 | P2RY14 (0.33) | CYP3A4NOTUM | |
| SCHEMBL8020721 | 0.72 | HTR2A (0.37) | — | |
| SCHEMBL8020717 | 0.72 | HTR2A (0.37) | — | |
| SCHEMBL7766440 | 0.72 | DAO (0.32) | FFAR4 | |
| SCHEMBL7766436 | 0.72 | DAO (0.32) | FFAR4 | |
| SCHEMBL8395000 | 0.70 | KDM1A (0.33) | — | |
| SCHEMBL8395002 | 0.70 | KDM1A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |