Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31675013 | 0.85 | LMNA (0.80) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31675008 | 0.84 | LMNA (0.77) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31675010 | 0.81 | LMNA (0.77) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7968011 | 0.80 | ALDH1A1 (0.56) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL27625364 | 0.77 | LMNA (0.66) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3207417 | 0.76 | LMNA (0.64) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL29979179 | 0.76 | LMNA (0.64) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6939616 | 0.74 | MEN1 (0.51) | KMT2AMEN1GAA | |
| SCHEMBL12417226 | 0.74 | LMNA (0.62) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9830210 | 0.73 | KMT2A (0.73) | LMNAALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |