Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037483 | 0.87 | MEN1 (0.59) | MEN1KMT2AALDH1A1POLBCYP1A2 | |
| SCHEMBL8040498 | 0.83 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8040471 | 0.83 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8037120 | 0.82 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6736692 | 0.74 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL7574943 | 0.73 | MEN1 (0.44) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL17095630 | 0.72 | POLB (0.73) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL8043322 | 0.72 | MEN1 (0.38) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5635430 | 0.71 | TDP1 (0.67) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL8038946 | 0.71 | MAPT (0.46) | ALDH1A1MAPTLMNATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110911-A | ADMINISTERING NEUROPROTECTANT/ANTICONVULSANT TO PATIENT | WARNER-LAMBERT COMPANY (US) | 2000-08-29 | — | — | US | disclosed |