Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040471 | 0.87 | MEN1 (0.49) | MEN1KMT2AHPGDRAB9ACRHBP | |
| SCHEMBL8040498 | 0.87 | MEN1 (0.49) | MEN1KMT2AHPGDRAB9ACRHBP | |
| SCHEMBL8037120 | 0.86 | MEN1 (0.47) | MEN1KMT2AHPGDRAB9ACRHBP | |
| SCHEMBL8038946 | 0.81 | MAPT (0.46) | L3MBTL1MAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL7567294 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2ARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8040494 | 0.79 | ACHE (0.55) | MEN1KMT2ARAB9AMCOLN3L3MBTL1 | |
| SCHEMBL8027126 | 0.74 | RAB9A (0.45) | MEN1KMT2ARAB9AMCOLN3L3MBTL1 | |
| SCHEMBL8037464 | 0.72 | HRH3 (0.45) | MEN1KMT2ACRHBPCRHR2MCOLN3 | |
| SCHEMBL8027121 | 0.72 | MEN1 (0.56) | MEN1KMT2AL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL8038941 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2AHPGDCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110911-A | ADMINISTERING NEUROPROTECTANT/ANTICONVULSANT TO PATIENT | WARNER-LAMBERT COMPANY (US) | 2000-08-29 | — | — | US | disclosed |