Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65057 | 0.85 | ALDH1A1 (0.65) | MITFALDH1A1KMT2APKMLMNA | |
| SCHEMBL65075 | 0.85 | ALDH1A1 (0.65) | MITFALDH1A1KMT2APKMLMNA | |
| SCHEMBL1229422 | 0.79 | MITF (0.46) | MITFALDH1A1KMT2APKMLMNA | |
| SCHEMBL12901769 | 0.79 | MITF (0.44) | MITFALDH1A1KMT2APKMLMNA | |
| SCHEMBL2358150 | 0.78 | KMT2A (0.71) | ALDH1A1KMT2ALMNACHRM1MAPK1 | |
| SCHEMBL16367393 | 0.75 | L3MBTL1 (0.46) | ALDH1A1PKMCHRM1MAPK1ATM | |
| SCHEMBL14004051 | 0.73 | ALDH1A1 (0.46) | MITFALDH1A1KMT2APKMLMNA | |
| SCHEMBL3303223 | 0.73 | MITF (0.55) | MITFALDH1A1KMT2APKMLMNA | |
| SCHEMBL11418348 | 0.72 | ALDH1A1 (0.59) | MITFALDH1A1KMT2APKMSOS1 | |
| SCHEMBL5405731 | 0.72 | MITF (0.65) | MITFALDH1A1KMT2APKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087358-A | BACTERICIDES TREATING PATHOGENIC INFECTIONS OF MYCOBACTERIA, CLOSTRIDIUM, CRYPTOSPORIDIUM OR HELICOBACTER AND MULTIDRUG-RESISTANT TUBERCULOSIS | PATHOGENESIS CORPORATION (US) | 2000-07-11 | — | — | US | disclosed |
| US-5668127-A | MYCOBACTERIUM TUBERCULOSIS, CLOSTRIDIUM | PATHOGENESIS CORPORATION (US) | 1997-09-16 | — | — | US | disclosed |