Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035686 | 0.86 | COMT (0.38) | TDP1POLBKDM4EL3MBTL1MAPT | |
| SCHEMBL8041629 | 0.85 | TDP1 (0.34) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL8028100 | 0.83 | L3MBTL1 (0.35) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL8040095 | 0.82 | ERN1 (0.37) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL8044817 | 0.81 | ALDH1A1 (0.35) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL8041621 | 0.80 | MEN1 (0.40) | POLBKDM4EMAPTMEN1KMT2A | |
| SCHEMBL8040090 | 0.79 | GAA (0.42) | KDM4EL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8038161 | 0.79 | ERN1 (0.38) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL8038657 | 0.78 | POLB (0.40) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8041625 | 0.78 | EGFR (0.35) | TDP1POLBKDM4EL3MBTL1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |