Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041621 | 0.90 | MEN1 (0.40) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8041264 | 0.88 | SMN1; SMN2 (0.41) | KMT2AMAPTALDH1A1 | |
| SCHEMBL8039106 | 0.82 | POLB (0.45) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8028096 | 0.78 | TDP1 (0.35) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8040095 | 0.78 | ERN1 (0.37) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8035095 | 0.77 | SPR (0.38) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8041629 | 0.76 | TDP1 (0.34) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8041234 | 0.76 | POLB (0.47) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8038161 | 0.75 | ERN1 (0.38) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8028100 | 0.75 | L3MBTL1 (0.35) | POLBKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |