Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207337 | 0.89 | ALDH1A1 (0.44) | ALDH1A1ALOX15METAP2KDM4EL3MBTL1 | |
| SCHEMBL14899077 | 0.84 | ALDH1A1 (0.41) | ALDH1A1ALOX15METAP2KDM4EL3MBTL1 | |
| SCHEMBL7208245 | 0.84 | ALDH1A1 (0.41) | ALDH1A1ALOX15KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL9637790 | 0.79 | ALDH1A1 (0.40) | ALDH1A1ALOX15KDM4EL3MBTL1HPGD | |
| SCHEMBL8411779 | 0.76 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2LMNADPP4FAP | |
| SCHEMBL11477925 | 0.74 | ALDH1A1 (0.41) | ALDH1A1ALOX15KDM4EL3MBTL1HPGD | |
| SCHEMBL22992426 | 0.73 | ALOX15 (0.37) | ALDH1A1ALOX15CADKDM4ESMN1; SMN2 | |
| SCHEMBL26931966 | 0.71 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HPGDLMNAHSD17B10 | |
| SCHEMBL14677522 | 0.71 | MGAM (0.41) | ALDH1A1ALOX15KDM4EL3MBTL1HSD17B10 | |
| SCHEMBL8277962 | 0.71 | ALDH1A1 (0.39) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100424-A | Process for the preparation of amino acetic acid esters with a tertiary hydrocarbon radical in the α-position | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | claimed |
| US-6100424-A | Process for the preparation of amino acetic acid esters with a tertiary hydrocarbon radical in the α-position | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |