Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.64 |
| ▸ | CFTR | P13569 | 1/20 | 0.64 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176557 | 0.88 | CYP19A1 (0.85) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL8176785 | 0.88 | CYP19A1 (0.55) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL8696779 | 0.80 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL6476580 | 0.78 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL144 | 0.78 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL27907795 | 0.78 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| Ammonia Solution, Strong SCHEMBL6000375 | 0.76 | SLC6A2 (0.95) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL3274982 | 0.76 | CYP19A1 (1.00) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL3434951 | 0.76 | SMN1; SMN2 (0.67) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL27490423 | 0.76 | ATM (0.44) | SLC6A2SLC6A4SLC6A3CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096754-A | N-3 substituted pyrimidin-4-ones with AII antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 2000-08-01 | — | — | US | disclosed |