Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700549 | 0.85 | CYP19A1 (0.66) | CYP19A1CYP2C19ALDH1A1MAPTHPGD | |
| SCHEMBL8703089 | 0.85 | CYP19A1 (0.43) | CYP19A1CYP2C19ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL8701933 | 0.85 | CYP19A1 (0.43) | CYP19A1ALDH1A1NPSR1L3MBTL1POLB | |
| SCHEMBL8627683 | 0.84 | CYP2C19 (0.48) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL8700864 | 0.81 | CYP19A1 (0.69) | CYP19A1CYP2C19CYP11B1CYP11B2 | |
| SCHEMBL8028167 | 0.80 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL1934617 | 0.80 | CYP2C19 (0.48) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL8176557 | 0.70 | CYP19A1 (0.85) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL8176785 | 0.70 | CYP19A1 (0.55) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL8699998 | 0.70 | CYP26A1 (0.44) | SLC6A2SLC6A4SLC6A3CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |