Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.43 |
| ▸ | RARG | P13631 | 6/20 | 0.43 |
| ▸ | RXRA | P19793 | 5/20 | 0.43 |
| ▸ | RARA | P10276 | 4/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026383 | 0.88 | CYP3A4 (0.42) | RARBRARGRXRARARARXRB | |
| SCHEMBL8028154 | 0.86 | RXRA (0.59) | RARBRARGRXRARARARXRB | |
| SCHEMBL6814364 | 0.82 | PDK2 (0.40) | RARBRARGRXRARARARXRB | |
| SCHEMBL8028178 | 0.82 | PTPN1 (0.50) | RARBRARGRXRARARACYP3A4 | |
| SCHEMBL6814439 | 0.82 | RARB (0.37) | RARBRARGRXRARARARXRB | |
| SCHEMBL8026629 | 0.81 | RARB (0.43) | RARBRARGRXRARARARXRB | |
| SCHEMBL6814372 | 0.78 | RXRA (0.49) | RARBRARGRXRARARARXRB | |
| SCHEMBL7421758 | 0.77 | RXRA (0.72) | RARBRARGRXRARARARXRB | |
| SCHEMBL6814070 | 0.76 | RARB (0.41) | RARBRARGRXRARARARXRB | |
| SCHEMBL8026052 | 0.75 | RARB (0.41) | RARBRARGRXRARARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |